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Use our Cookie Bot to quickly find your most popular choices. Adblock users get a better user experience.[Experimental study of cefotaxime in oral candidiasis in mice].
Cefotaxime (CTX) is effective against Candida albicans, but its activity against other Candida species remains unclear. The purpose of this study was to evaluate the efficacy of CTX against oral candidiasis in mice. Mice were infected orally with C. albicans, C. tropicalis, C. glabrata, C. guilliermondii or C. parapsilosis. They were then treated orally with CTX at 50, 75 or 100 mg/kg, or fluconazole (FLC) at 75 mg/kg, either daily or twice daily. FLX was used as the standard drug. Treatment was continued for 3 or 7 days. The efficacy of both treatments was evaluated by the severity of oral mucosal inflammation and the
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